The file p1spi.dll belongs to the Spicall Dynamic Link Library, which is part of the BearPaw 1200 driver software from Mustek. BearPaw 1200 is a color flatbed scanner. Driver software is what allows you to connect hardware, like this scanner, to your computer.
Without the driver software, your computer cannot send commands to the scanner. If you get an error with the ep1spi dynamic link library listed, you need to take action to get your scanner working again. One option is to reinstall the drivers for the scanner. You can also just clean your registry.
ZookaWare PC Cleaner will do the job for you. Your registry is a complicated database that has thousands of entries pointing to every piece of every program installed on your computer. Making a mistake while editing your registry could disable your computer, leaving you with expensive repair bills. Instead, run ZookaWare PC Cleaner and we’ll find and fix every problem in your registry, guaranteed. You can concentrate on scanning pictures instead of scanning your hard drive.