s11thk32.dll is one of the Systems from the Synth Core R2.0 Synthesizer, particularly the Synth Core R2.0 Midi Interface Driver. Drivers usually communicate with the device, in this case a synthesizer, through a subsystem to which your hardware connects.
Since drivers all depend on hardware and are operating system specific, DLL’s associated with systems for drivers can be misplaced during installation or fragmented pieces are abandoned in the registry during unsuccessful un-installations.

If you get a message like this once and never heard from it again, don’t be confused about the fact that you should take action. These files seem innocent enough and may only be causing momentary disruptions, but they are a sign of possible registry overload. Microsoft registries have not evolved at the rate that their Office Suite products have.

Windows registries eventually need to be scanned so the suspicious items are quarantined and removed if necessary.  ZookaWare PC Cleaner is the best known safe and affordable software out there. Visit them today for an initial free scan and learn about their unique guarantee.

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